Posted by VIncent_QC on January 21, 2009, at 7:18:33
Hi Everyone,
Some news from me... ;-)I'm on the Manerix(Moclobemide) since yesterday. 300mg/day for 14 days...It's a temporary solution...After we will see if I will get more well and if we up the dose to 600mg or more.
At the same time, someone else start a thread on this board about the possibilities to obtain a drug from another country in the Canada...Well it's where the word (Temporary) apply in my post...
My Doctor and myself are looking into a way to get some Marplan in Canada, since the Marplan seem to be more good than the newer Nardil, that I already try back in 2007. My PDoc is used to get some not approved drugs to treat psychotics diseases from the States to the Canada, but he also explain to me the whole process...
To be able to obtain a drug that is not approved in the Canada, the pharmaceutical company,who make the drug in the other country, have to be represented in the Canada and have an office in the Canada... The PDoc send the prescription to that compagny in the Canada and they import the drug in the Canada...He applies this method often for a specific drug to treat people with schizophrenia (I don't remember the name of the drug)...but it's a good drug not approved and sale in the Canada...
So we plan to get some Marplan in the Canada like this...but the main problem is that I look on the Internet who own the Marplan patented and the compagny name "Oxford Pharmaceutical Services Inc.) don't seem to have an office in the Canada or the equivalent. Before, Marplan was made by Hoffmann-La Roche, well represented in the Canada...but "Oxford" is acquiring ownership of the NDA (New Drug Application, the application needed to get a new drug approved in the United States by the Food and Drug Administration)...
So I'm not sure if my PDoc will be able to get some Marplan for me...
We talk also about the EMSAM patch...it's very expensive but they sell them in the Canada, but mostly of the Doctors and PDoc are not aware of this, my new PDoc seem to be the only one to know it!!! Strange...anyway, we are looking for the Emsam patch also in Canada...My PDoc have some research to do, find the pharmaceutical company who produce it in the Canada...or at least who import it in the Canada...
Well, that's complicated...Since I answer a little bit to the Parnate and Nardil before, but I encounter too much blood pressure problems (mean that i'm very sensitive to the NE effect of these drugs) for the social phobia, the PDoc think that the only way I will improve will be from a MAOI's and probably an irreversible ones...And the only other option left in that field is the Marplan...Oral selegiline will not be a good solution, since it's more a Type-B of MAO, I will get just the stimulation effect of it...with my gastric by-pass, we don'T know exactly what will be the effect on me, and also the Type-B of MAO seem to not be a good way to treat the social phobia and anxiety problem, it's apply more to the people with depressive illiness with a no anxiety symptom, a lack of energy and motivation...at the same time, I don't have energy and I lack a lot of motivation, so maybe it can be effective just to treat that conditions...
We forget every TCA's tries possibilities, since they all have some potent effects on the NE and they all cause some weight gain as well as more daytime sedation... I don't need to add extra pounds and sleep more at daytime...
So that's it...Manerix at 300mg, in case I will improve a little bit...if not, after 14 days, we will talk about the possibilities to have the Marplan or the EMSAM patch. If it's not possible to get them, at least the Marplan, since the EMSAM patch is a lot expensive and I can't afford it, we will increase the Manerix to a 600mg/day...until we reach the 1200mg...and if it's not helping at this dosage, I will probably give to the Nardil a second try...maybe pushing the Nardil to more than 90mg/day and remain at this dose for more than 2 weeks, even if the orthostatic hypotension is hard to tolerate, will help? Who know... maybe the Manerix will help also...???If I don't give it a try I will never know...
I was not really excited about the Manerix, I know it's not worth a lot here, and for what I read on this board, that's not seem to be a terrible choice...but I keep in minds that it's just a temporary solution...I don't put a lot of pressure on my Manerix try and I don't want to push to hard the dosage also..this time, I go with the PDoc indications and I will follow them...
So i'm in a stand-by mode...we will see what will happen soon ;-)
For now, on the Manerix, 150mg X 2times day, I feel a little bit strange. When I take my first 150mg pill last evening, I feel a strange effect like a "rush" of adrenaline inside my head, like I will have to do something very hard or I Will live something very exciting...that's weird...It seem to be more stimulating than the Parnate...but don't affet my heart beat...maybe it's just a psychological effect...who know!...This morning, I take my 150md pill and I feel nothing at all...Anyway...
Well thanks everyone...and if someone know if "Oxford" compagny is represented in the Canada or have an office or the equivalence...or if someone know how to obtain the Marplan in the Canada, don't be shy and post an answer to my questions ;-)
Bye!
Vincent ;-)
poster:VIncent_QC
thread:875257
URL: http://www.dr-bob.org/babble/20090104/msgs/875257.html