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Other DA agonists: piribedil, lisuride. Abilify?

Posted by Brainbeard on June 4, 2010, at 2:19:58

In reply to Re: Advice please re. clomipramine/anafranil » bulldog2, posted by hopefullynow on June 4, 2010, at 2:11:39

There are other dopamine agonists worth looking into:

There's piribedil, brand name Trivastal, Servier's D2/3-agonist, which doesn't cause sleep attacks unlike most other synthetic dopamine agonists and also has some cognitive enhancing qualities. It may not be a very strong proilactin suppressor though.

Then there's lisuride, an ergot-derived dopamine agonist that doesn't cause cardiac valve trouble like most ergot derived DA agonists can, and which is also a potent 5HT1A-agonist, which potentiates SRI. Lisuride is actually a chemical cousin of LSD, but without the hallucinogenic effects of the latter.

Finally, aripiprazole (Abilify) has also shown to be able to counter drug-induced hyperprolactinemia.


Current meds: 10mg melitracene + 0.5mg flupentixol; sertraline 100mg; amitriptyline 25mg; gabapentin (Neurontin) 300mg; melatonin 0.3mg. PRN: diazepam (Valium) 2.5-5mg.


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URL: http://www.dr-bob.org/babble/20100524/msgs/949895.html