Posted by bulldog2 on June 6, 2010, at 10:53:12
In reply to Other DA agonists: piribedil, lisuride. Abilify?, posted by Brainbeard on June 4, 2010, at 2:19:58
> There are other dopamine agonists worth looking into:
>
> There's piribedil, brand name Trivastal, Servier's D2/3-agonist, which doesn't cause sleep attacks unlike most other synthetic dopamine agonists and also has some cognitive enhancing qualities. It may not be a very strong proilactin suppressor though.
>
> Then there's lisuride, an ergot-derived dopamine agonist that doesn't cause cardiac valve trouble like most ergot derived DA agonists can, and which is also a potent 5HT1A-agonist, which potentiates SRI. Lisuride is actually a chemical cousin of LSD, but without the hallucinogenic effects of the latter.
>
> Finally, aripiprazole (Abilify) has also shown to be able to counter drug-induced hyperprolactinemia.Brainbeard some excellent advice. Now you being a genius I'm sure you can answer this. Which dopamine receptor is implicated with raising or lowering prolactin. If I knew the answer to that I could make a good choice. I tried trivetal and it had a nice feel but pooped out rather quickly.
If abilify at low doses could bring down the prolactin it would make a great choice as it is also an ad augmentor.
So tell me about this lisuride. There's a lot of talk in meds about this agonist. Does it strongly hit the prolactin receptors? What other good things does it do?
The impression I get is dostinex, miraprex and requip are good prolactin suppressors. But I would like to pick one that also has some ad properties. Sorry for the long post.
poster:bulldog2
thread:949082
URL: http://www.dr-bob.org/babble/20100604/msgs/950099.html