Posted by Larry Hoover on November 30, 2003, at 7:58:18
In reply to Q's on the usefulness of the phosphatdyls » Larry Hoover, posted by DSCH on November 29, 2003, at 14:40:45
> Larry, care to discourse on what the body does with the various phosphatidyls and how they can help? Francesco's pdoc says they don't cross over the BBB, is he correct? What would be a rule of thumb for starting dose (in mgs of the constituents)? Which disorders are most likely linked to problems with them?
I want to add.....
One of the "theories" about how neurotranmsitter deficiencies may develop in the brain involves faulty vescicle construction.
Just as each neuron is surrounded by a lipid bilayer membrane, tiny versions of that same bilayer (analogous to bubbles, I guess), are used to store neurotransmitters, adjacent to the synapse. Those bubbles are called vescicles. In response to an activating signal, the vescicle bubble moves to the surface of the cell, and it "bursts" open, but that's really more like the smaller bubble joining the bigger one (if you've ever had a bubble bath, you've undoubtedly watched this happen). Anyway, the vescicle theory of neurotransmitter depletion invokes the idea that the vescicles are not constructed properly (raw material shortages? phospholipid synthesis problems?), and they leak....permitting exposure to degredative enzymes like COMT and MAO.
I'm a strong believer in supplying raw materials to the body, and I'm a strong believer in my body knowing what to do with them, once supplied. If you are not phospholipid deficient, then supplements are merely (somewhat expensive) energy sources, supplying nine calories per gram, just like other lipids in food. However, if you do have biochemical inefficiencies, or dietary deficiencies......you can connect the dots.
Lar
poster:Larry Hoover
thread:283090
URL: http://www.dr-bob.org/babble/alter/20031122/msgs/285187.html