Posted by raybakes on October 29, 2004, at 11:54:38
In reply to Re: Bowel toxins,enzyme peptide conversion of aminos? » raybakes, posted by Larry Hoover on October 29, 2004, at 8:35:29
> > if too many detoxification enzymes are used up clearing bowel toxins, there's not enough to regulate neurotransmitters..
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> I can't think of a single case where that is true.Hi Lar, I was thinking of sulphation and glucuronidation in particular, because of the work on the brain-gut connection with autistic children. I think pathogens also secrete sulphatase and glucuronidase that split conjugated metabolites and toxins, and also break down the glycoproteins that hold the extracellular matrix of the gut wall together. Also methylation has a strong link with a healthy gut...
"The patients with IBD had nearly a six-fold increased incidence of hyperhomocysteinemia - having homocysteine levels above the normal range - compared to controls."
Autism and gastrointestinal symptoms., Horvath K, Perman JA., Current Gastroenterology Reports 2002 Jun;4(3):251-8
" . . . Recent clinical studies have revealed a high prevalence of gastrointestinal symptoms, inflammation, and dysfunction in children with autism. Mild to moderate degrees of inflammation were found in both the upper and lower intestinal tract. In addition, decreased sulfation capacity of the liver, pathologic intestinal permeability, increased secretory response to intravenous secretin injection, and decreased digestive enzyme activities were reported in many children with autism. Treatment of digestive problems appears to have positive effects on autistic behavior. These new observations represent only a piece of the unsolved autism "puzzle" and should stimulate more research into the brain-gut connection. "
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> > I'm not sure they would directly aid these enzymes, but it would certainly allow more nutrients available to synthesize them - think it's probably true that bacteria and yeast can degrade important amino acids.
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> Can, but don't have time to do so. Moreover, they much prefer dealing with the energy available in all those carbs and sugars passing by. They turn to amino acid metabolism only when they're starving.
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my line of thought was that they might turn the catecholamines into tyramine, melanin and quinones, making them unavailable for neurotransmitters. If they don't then radicals like superoxide generated by immune cells during gut dysbiosis, might oxidise them anyway? What do you think?Ray
poster:raybakes
thread:407758
URL: http://www.dr-bob.org/babble/alter/20041022/msgs/408753.html