Posted by Sarah T. on April 16, 2005, at 23:16:18
In reply to Re: KaraS, another question for you » Sarah T., posted by KaraS on April 15, 2005, at 19:38:24
KS: > > > > > I think you're right that Surmontil is fairly easily mixed with other meds. I don't think you have anything to lose by trying either of these two drugs at low doses. The one advantage that doxepin has over Surmontil is that it is less anticholinergic. I'm very afraid of anything that's going to dumb me down at all. (I'm not feeling terribly sharp these days to begin with!) >
ST: Thanks for letting me know that Doxepin is less anticholinergic than Surmontil. I do remember seeing one of those charts rating various meds according to their adverse effects, but I haven't seen the chart in a while. I'll have to do a search on it.
KS:>> I was thinking in terms of mixing Surmontil (or doxepin?) with selegiline + DLPA. I had been waiting for the Ensam patch but since I had the anxiety meltdown a couple of months ago, I'm afraid I wouldn't be able to tolerate the patch unless I'm able to combine it with something very anxiolytic. (Initially when I tried selegiline it made me sleepy but after the third or fourth day, it still made me feel tired initially but started producing more of a stimulant type effect about 8-9 hours after I took it.) But maybe you're right, maybe the transdermal delivery system will reduce the side effects and make it easier to tolerate for both of us. Then maybe they'll make a lot of psych meds in patch form and life will get much easier for many of us. (I'm trying to think positively, can you tell?) > Kara >
ST: I wonder why you got tired from the Selegiline at first. How many milligrams did you take? When you felt the stimulant effect 8-9 hours later, perhaps it was one or more of those metabolites kicking in. I am curious about your initial fatigue on what is supposedly a stimulating medicine. One reason for my interest is that, when I developed tolerance to Dexedrine, that tolerance manifested primarily as fatigue (sometimes extreme) and, at times, a zombie-like affect. I assumed that my presynaptic receptors had become overly efficient at dopamine reuptake. Initially, my doctor told me to take more, but that was the worst thing to do! I became completely immobilized when I increased the daily dose, or if I took too many milligrams at once, or if I took one dose too close to the next one.
poster:Sarah T.
thread:478017
URL: http://www.dr-bob.org/babble/alter/20050414/msgs/485319.html