Posted by KaraS on April 19, 2005, at 20:39:20
In reply to Re: Melatonin etc. » KaraS, posted by Sarah T. on April 19, 2005, at 0:13:58
> ST: Hi Kara. This evening I read that melatonin is a substrate of the cytochrome P450 1A2 enzyme and that estradiol inhibits that same enzyme. So, if estradiol levels are high, then melatonin levels would be increased. And then, there is so much interplay between the hormones and neurotransmitters. Ah, it gets so complicated. I just want something that works!
>Hi, I hear you about your frustration. I think I've given up on a magic cure. I'd be satisfied these days with a few meds and supplements that when taken together, will treat most of my problems so that I can lead a decent life.
That's amazing about the estrogen and melatonin connection. I hadn't known that. You really can effect a lot of different systems when you introduce somthing new into your body. You were wise to do the research.
> KS: The doxepin doesn't really make me any more organized - though it controls the anxiety ansd so allows me to function and then get some things done. The anticholinergic effects are minor at the 25 mg. dosage but I would love to be able to find something else that would help with concentration etc. I will probably try DMAE and the selegiline for that as well. > K >
>
> ST: That's a really good point about the anxiety affecting the ability to get things done. Perhaps some of my disorganization is caused by anxiety. Can you tell me what DMAE is? I should know that, but I don't. You don't mean DHEA, do you?DMAE is a supplement. The DMAE stands for dimethylaminoethanol. It is very similar to choline - the only difference is one methyl group if I remember correctly. It's a supplement that is in all of the natural treatments for ADD. I don't know if it lives up to all of the hype but it may be worth a try to help with organization issues. Tamara was taking it for a while and she may still be taking it if you want to ask her about it. It can increase anxiety so start out with smaller doses (which I'm sure you would anyway).
Here are a couple of links if you're interested in reading more about it. One of them is from Dr. Sahelian's site. He is extremely conservative in dosage so keep that in mind.
http://www.raysahelian.com/dmae.html
Let me know what you think.Kara
poster:KaraS
thread:478017
URL: http://www.dr-bob.org/babble/alter/20050414/msgs/486638.html