Posted by JLx on May 8, 2005, at 11:25:55
In reply to Re: PEA -- where to find... » JLxx, posted by Chairman_MAO on May 5, 2005, at 20:00:42
> Just buy PEA HCl from a chemical supply company? Even with rediculous chemical supply house markup, it still cost me like $40 for 100g or something like that. Catalogs.google.com is a good start, and tons of them have it. Just gotta find one that will sell to you.
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> I am warning you guys that PEA is not benign. It is an extremely powerful endogenous neuromodulator that should be treated with respect. You can easily put yourself near psychosis by taking too much of it over a relatively short period of time. The problem is with MAO-B inhibited, it accumulates in the brain, yet you only feel its action for a short while. Thus, more is taken, and the cycle repeats. I also never found it that pleasurable for any extended period of time. For posterity, I once tried IVing 60mg of it. I got a nice rush. I did it again the next day, and felt incredibly anxious and dysphoric. It definitely is not amphetamine.
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> If one supplements with it and an MAO-B inhibitor, I recommend starting at 5-10mg per day and working up slowly. You can get a good antidepressant effect, I'm sure; just tread with caution.I have no desire to get high, and I certainly don't want to become psychotic. I've never taken an MAOI drug and I don't care to but I'm curious about PEA. I hurt my foot last summer and couldn't do my usual fitness walking and really noticed my depression increased. And God knows, I've loved chocolate all my life, especially in times of stress when it really does make me feel better. But the trouble there of course is the fat and sugar.
You say, "I recommend starting at 5-10mg per day and working up slowly." Why work up at all? And to what?
This 1994 article, http://www.findarticles.com/p/articles/mi_m1430/is_n11_v16/ai_15654206 quotes a doctor doing animal PEA research, "as PEA is administered the animals need less, not more."
I was just reading a post about the extremely short half life of PEA, and that is why people are taking selegeline with DLPA, to prolong it. Ok, but what is the difference between increasing PEA through exercise? Exercise relieves depression not just for a few minutes, but overall. Not for everyone, I know, but it seems to for me.
So could there be a anti-depressive benefit of taking blue green algae or raw chocolate in the amount to provide approx 10 mg of PEA a day? And what could be the downside?
JL
poster:JLx
thread:488304
URL: http://www.dr-bob.org/babble/alter/20050414/msgs/495170.html