Psycho-Babble Medication Thread 499967

Shown: posts 1 to 25 of 38. This is the beginning of the thread.

 

Why are evenings worse?

Posted by Maxime on May 19, 2005, at 15:30:09

Hello.

I find that my depression takes over in the evening. I try to keep myself distracted by reading or writing, but still I feel a wave of sadness come over me. If I call a friend, I still feel very alone.

Is there a biochemical reason for this? Would it have anything to do with cortisone levels?

Sometimes I work on CBT exercises from the Feel Good Handbook to see if it will help, but so far it hasn't.

It really is a significant drop in my mood. When I can cry .... I do. Right now I can't cry. I don't feel any anxiety or anything just EXTREME sadness.
This has always been the case for me. It's like my anti-depressant just stops working.

Anyone have any input? Sometimes I don't feel very safe at night and I end up having to call a hotline. A few nights ago I went to the hospital, only to be sent home and feeling even worse.

Help?

Maxime

 

Re: Why are evenings worse? » Maxime

Posted by ed_uk on May 19, 2005, at 15:38:37

In reply to Why are evenings worse?, posted by Maxime on May 19, 2005, at 15:30:09

Hi Maxi,

>It's like my anti-depressant just stops working.

I wonder if it would help if you took the Parnate in divided doses. Will you try taking 40-50mg twice a day?

Ed xxxx

 

Re: Why are evenings worse?

Posted by Maxime on May 19, 2005, at 15:48:35

In reply to Re: Why are evenings worse? » Maxime, posted by ed_uk on May 19, 2005, at 15:38:37

Yes well today I forgot the second dose. But surely after I take it for several weeks at a therapeutic dose there will be enough built up in my body to last the day? This night time problem has been going on for years. I hate it.

Maxime


> Hi Maxi,
>
> >It's like my anti-depressant just stops working.
>
> I wonder if it would help if you took the Parnate in divided doses. Will you try taking 40-50mg twice a day?
>
> Ed xxxx
>
>

 

Re: Why are evenings worse? » Maxime

Posted by 4WD on May 19, 2005, at 16:29:36

In reply to Why are evenings worse?, posted by Maxime on May 19, 2005, at 15:30:09

> Hello.
>
> I find that my depression takes over in the evening. I try to keep myself distracted by reading or writing, but still I feel a wave of sadness come over me. If I call a friend, I still feel very alone.
>
> Is there a biochemical reason for this? Would it have anything to do with cortisone levels?
>
> Sometimes I work on CBT exercises from the Feel Good Handbook to see if it will help, but so far it hasn't.
>
> It really is a significant drop in my mood. When I can cry .... I do. Right now I can't cry. I don't feel any anxiety or anything just EXTREME sadness.
> This has always been the case for me. It's like my anti-depressant just stops working.
>
> Anyone have any input? Sometimes I don't feel very safe at night and I end up having to call a hotline. A few nights ago I went to the hospital, only to be sent home and feeling even worse.
>
> Help?
>
> Maxime
>

Maxime,

I think it must be biochemical. It is the exact opposite for me. I wake up feeling bad, am very anxious in the mornings and most of the day (unless I take Klonopin). I'm also tired and unmotivated and anhedonic during the day.

AT night, however, maybe at about 8 or sometimes not til 11, I begin to feel good. No depression, no anxiety, no tiredness. I could enjoy going to the gym and working out. But of course, it's bedtime.

I don't get it. How can it just change like that during the day or night?

You must dread when it begins to get dark. Do you think it would help to get one of those lights like for SAD? Have you asked your doctor about this? He/she probably scratched his/her head and said "hmmm, I don't know."

Have you had your cortisol levels checked? Mine is extremely high. Maybe yours drops at night?

Marsha

 

Re: Why are evenings worse? » Maxime

Posted by ixus on May 19, 2005, at 17:01:49

In reply to Why are evenings worse?, posted by Maxime on May 19, 2005, at 15:30:09

> Hello.
>
> I find that my depression takes over in the evening. I try to keep myself distracted by reading or writing, but still I feel a wave of sadness come over me. If I call a friend, I still feel very alone.

Hi Maxime,
I had the same problems when I was on Parnate. But not always. I think you feel withdrawal effects from high dose of Parnate .
/ixus

 

Re: Why are evenings worse? » Maxime

Posted by ed_uk on May 19, 2005, at 17:31:56

In reply to Re: Why are evenings worse?, posted by Maxime on May 19, 2005, at 15:48:35

Hi Maxi!

>Yes well today I forgot the second dose.

Oops :-S

>But surely after I take it for several weeks at a therapeutic dose there will be enough built up in my body to last the day?

The MAO inhibition will last all day. Some people claim that Parnate has a short-lived stimulant-like effect that lasts a few hours. I don't know how much truth there is in this.

Ed xxxx

 

Re: Why are evenings worse?

Posted by mike13 on May 19, 2005, at 17:39:35

In reply to Re: Why are evenings worse? » Maxime, posted by 4WD on May 19, 2005, at 16:29:36


>
> I think it must be biochemical. It is the exact opposite for me. I wake up feeling bad, am very anxious in the mornings and most of the day (unless I take Klonopin). I'm also tired and unmotivated and anhedonic during the day.
>
> AT night, however, maybe at about 8 or sometimes not til 11, I begin to feel good. No depression, no anxiety, no tiredness. I could enjoy going to the gym and working out. But of course, it's bedtime.
>
> I don't get it. How can it just change like that during the day or night?
>
> You must dread when it begins to get dark. Do you think it would help to get one of those lights like for SAD? Have you asked your doctor about this? He/she probably scratched his/her head and said "hmmm, I don't know."
>
> Have you had your cortisol levels checked? Mine is extremely high. Maybe yours drops at night?
>
> Marsha

Exact same for me, I always feel good during the night..

 

Re: Why are evenings worse?

Posted by Maxime on May 19, 2005, at 17:53:22

In reply to Re: Why are evenings worse?, posted by mike13 on May 19, 2005, at 17:39:35

Maybe it's because I have no Dexedrine in my system by night time? But then that makes me wonder ... is the Parnate doing anything - LOL!? ACK! I can't handle this. It really is painful.

Maxime

 

Re: Why are evenings worse?

Posted by bart on May 19, 2005, at 18:57:40

In reply to Re: Why are evenings worse? » Maxime, posted by 4WD on May 19, 2005, at 16:29:36

I'm the same exact way as you, I get reved up at night and depressed and anti social during the day

 

Re: Why are evenings worse?

Posted by Phillipa on May 19, 2005, at 19:41:02

In reply to Re: Why are evenings worse?, posted by bart on May 19, 2005, at 18:57:40

I feel better at night. I wake up depressed and anxious about what I will do that day. At night time there are no expectations for me. And I think it's worse at night for a person if they are all alone. Fondly, Phillipa

 

Re: Why are evenings worse? » Maxime

Posted by MidnightBlue on May 19, 2005, at 19:41:27

In reply to Why are evenings worse?, posted by Maxime on May 19, 2005, at 15:30:09

Maxime,

Hugs to you my friend.

>
> I find that my depression takes over in the evening. I try to keep myself distracted by reading or writing, but still I feel a wave of sadness come over me. If I call a friend, I still feel very alone.

Well, I sort of feel that way right now, but I also feel exhausted, and all I did today was cook dinner. Usually I "come to" for a bit late at night say 9 p.m. or later. Mornings are very slow going for me.
>
> Is there a biochemical reason for this? Would it have anything to do with cortisone levels?
>
> Sometimes I work on CBT exercises from the Feel Good Handbook to see if it will help, but so far it hasn't.

Do you think doing the CBT exercises is depressing? I tried some once and it made me feel worse.
>
> It really is a significant drop in my mood. When I can cry .... I do. Right now I can't cry. I don't feel any anxiety or anything just EXTREME sadness.

I've actually been crying a bit more the last couple of weeks. I guess that means I'm better because I can at least feel the pain I'm not frozen.

> This has always been the case for me. It's like my anti-depressant just stops working.

I felt that way when I first took Wellbutrin and it worked for me. I was on the regular form there was no extended dose and it would wear out on me kind of like Ritalin did on my daughter.

> Anyone have any input? Sometimes I don't feel very safe at night and I end up having to call a hotline. A few nights ago I went to the hospital, only to be sent home and feeling even worse.

I'm glad you are at least calling help lines. I'm sorry the hospital turned you away. I'll never forget the times I sat in a pdocs office thinking if he only knew what was going through my head he wouldn't let me out of here!
>
> Help?

I'll try to be here for you as much as I can. I have some other health issues that are giving me fits right now. I must start taking blood pressure meds and I am in an utter panic about it. My fish oil is tearing up my stomach and I'm hurting all over.

Can you set an alarm to go off in the afternoon to remind you to take an afternoon dose of Parnate? That is the right drug isn't it? My brain is so scattered lately.

Hugs,

MidnightBlue

 

Re: Why are evenings worse?

Posted by vivi on May 19, 2005, at 20:13:59

In reply to Why are evenings worse?, posted by Maxime on May 19, 2005, at 15:30:09

> Hello.
>
> I find that my depression takes over in the evening. I try to keep myself distracted by reading or writing, but still I feel a wave of sadness come over me. If I call a friend, I still feel very alone.
>
> Is there a biochemical reason for this? Would it have anything to do with cortisone levels?
>
> Sometimes I work on CBT exercises from the Feel Good Handbook to see if it will help, but so far it hasn't.
>
> It really is a significant drop in my mood. When I can cry .... I do. Right now I can't cry. I don't feel any anxiety or anything just EXTREME sadness.
> This has always been the case for me. It's like my anti-depressant just stops working.
>
> Anyone have any input? Sometimes I don't feel very safe at night and I end up having to call a hotline. A few nights ago I went to the hospital, only to be sent home and feeling even worse.
>
> Help?
>
> Maxime
>
I feel worse at night too. But I think it might be because I am coming off the Dex. It is starting to make me depressed when it wears off. I then end up taking an Ambien to go to sleep. How much Dexedrine do you take? I remember you mentioning that you have taken it. Do you still? Keep calling your friends, you do not need to be alone. Are you going to be seeing your Doctor soon? Call and schedule an appointment:)
ViviLeigh

 

Re: Why are evenings worse? » Maxime

Posted by Jakeman on May 19, 2005, at 21:59:25

In reply to Why are evenings worse?, posted by Maxime on May 19, 2005, at 15:30:09

For me, mood and energy starts to decline in mid-afternoon and gradually gets worse. It's almost as if an invisible hand is pushing down on me. I've tried adjusting the times I take meds and vitamins with a small bit of success but I feel something bigger is going on. Maybe something's out of wack hormonally or with glucose metabolism. Drinking a Coke picks me back up for a short time. I have trouble getting any doctor to take me seriously about this though.

best wishes- J

 

Re: Why are evenings worse?

Posted by Maxime on May 19, 2005, at 22:44:31

In reply to Re: Why are evenings worse?, posted by vivi on May 19, 2005, at 20:13:59

I just saw my pdoc. I only take 10 mg of Dexedrine a day which isn't much. I don't think my pdoc will be much help. He will tell me to find something fun to do at night. I think the dexedrine does make me crash.

Maxime


> > Hello.
> >
> > I find that my depression takes over in the evening. I try to keep myself distracted by reading or writing, but still I feel a wave of sadness come over me. If I call a friend, I still feel very alone.
> >
> > Is there a biochemical reason for this? Would it have anything to do with cortisone levels?
> >
> > Sometimes I work on CBT exercises from the Feel Good Handbook to see if it will help, but so far it hasn't.
> >
> > It really is a significant drop in my mood. When I can cry .... I do. Right now I can't cry. I don't feel any anxiety or anything just EXTREME sadness.
> > This has always been the case for me. It's like my anti-depressant just stops working.
> >
> > Anyone have any input? Sometimes I don't feel very safe at night and I end up having to call a hotline. A few nights ago I went to the hospital, only to be sent home and feeling even worse.
> >
> > Help?
> >
> > Maxime
> >
> I feel worse at night too. But I think it might be because I am coming off the Dex. It is starting to make me depressed when it wears off. I then end up taking an Ambien to go to sleep. How much Dexedrine do you take? I remember you mentioning that you have taken it. Do you still? Keep calling your friends, you do not need to be alone. Are you going to be seeing your Doctor soon? Call and schedule an appointment:)
> ViviLeigh
>
>

 

Re: Why are evenings worse? » Jakeman

Posted by Maxime on May 19, 2005, at 22:49:26

In reply to Re: Why are evenings worse? » Maxime, posted by Jakeman on May 19, 2005, at 21:59:25

My blood sugar. I bet that is part of the problem. I must start taking my chromium pills again and see if that helps. I'll let you know. :-)

Maxime


> For me, mood and energy starts to decline in mid-afternoon and gradually gets worse. It's almost as if an invisible hand is pushing down on me. I've tried adjusting the times I take meds and vitamins with a small bit of success but I feel something bigger is going on. Maybe something's out of wack hormonally or with glucose metabolism. Drinking a Coke picks me back up for a short time. I have trouble getting any doctor to take me seriously about this though.
>
> best wishes- J

 

Re: Why are evenings worse?

Posted by Declan on May 19, 2005, at 23:22:15

In reply to Re: Why are evenings worse?, posted by Maxime on May 19, 2005, at 22:44:31

Hi
I suppose 10mg isn't much but its not surprising you should feel worse as it wears off, just as you feel better when it works.
Declan

 

Re: Why are evenings worse?

Posted by FredPotter on May 20, 2005, at 0:14:17

In reply to Re: Why are evenings worse?, posted by Declan on May 19, 2005, at 23:22:15

I think you might be wrong to blame biochemistry for this. Although biochemistry will alter with mood, it may not be the cause. We're biochemical and we're social. We're physical *and* we're spiritual. But thanks Maxime for bringing this up because I have it too. I'm 58 and have only recently discovered that people are basically friendly (perhaps it's because I now live in NZ!). What's more I need to be around people. So when I'm at work I'm motivated, social and happy, broadly speaking. I go home happy too.

But I live alone since my wife left 4 years ago(with the kids). Every evening at first I enjoy the freedom but gradually a dread builds up. A dread and hopelessness that I'm not necessary to anyone and I'm all alone, washed up. Damn this nuclear family age. If I have to go out to play in my band I really come to life.

I believe for me that this is a simpler explanation than talking about drugs and biochemical imbalance. I take Celexa but suspect it doesn't do much. Xanax is powerless over "the evening feeling" too. I sometimes have a compulsion to prove that I can go it alone in life. However I suspect none of us can, because we're social animals. Perhaps even hermits pay a high emotional price for their freedom. Or perhaps the pain of feeling alone and un-needed is less than the pain outside in the world.

Life's a bugger really

Fred

 

Re: Why are evenings worse? » Maxime

Posted by jerrympls on May 20, 2005, at 1:33:57

In reply to Why are evenings worse?, posted by Maxime on May 19, 2005, at 15:30:09

> Hello.
>
> I find that my depression takes over in the evening. I try to keep myself distracted by reading or writing, but still I feel a wave of sadness come over me. If I call a friend, I still feel very alone.
>
> Is there a biochemical reason for this? Would it have anything to do with cortisone levels?
>
> Sometimes I work on CBT exercises from the Feel Good Handbook to see if it will help, but so far it hasn't.
>
> It really is a significant drop in my mood. When I can cry .... I do. Right now I can't cry. I don't feel any anxiety or anything just EXTREME sadness.
> This has always been the case for me. It's like my anti-depressant just stops working.
>
> Anyone have any input? Sometimes I don't feel very safe at night and I end up having to call a hotline. A few nights ago I went to the hospital, only to be sent home and feeling even worse.
>
> Help?
>
> Maxime
>
HI Maxime

I'm the same way. But I get more anxious and lonely than sad. Part of it for me, I think, is that my Dexedrine has worn off - but I also think that cortisol levels have some impact as well. If I am not mistaken, cortisol production/release? is *supposed* to taper down at night staying at lower levels throughout the night and then gradually tapering back up in the morning. I THINK?? But I wouldn't blame it all on cortisol - medication timing, hormones, melatonin function, etc all come into play. I had my cortisol levels checked pretty thoroughly a while back and they found that my levels were consistently LOW! Which kinda makes sense - since my depression is more anhedonic/lethargic, etc.

I know scientists are looking at meds that stabilize the cortisol system - otherwise known as the HPA axis. My pdoc think that my HPA system is out of balance - but haven't found any suitable meds to try to get it back on track.

I also notice that I get more lethargic and depressed in the spring/summer months. Exact opposite from usual SAD. Not sure why that would be? But I can certainly feel a bit of mode improvement in the Fall & Winter months.

Anyway, hope this helps..
Jerry

 

Re: Why are evenings worse? » FredPotter

Posted by jerrympls on May 20, 2005, at 1:40:20

In reply to Re: Why are evenings worse?, posted by FredPotter on May 20, 2005, at 0:14:17

> I think you might be wrong to blame biochemistry for this. Although biochemistry will alter with mood, it may not be the cause. We're biochemical and we're social. We're physical *and* we're spiritual. But thanks Maxime for bringing this up because I have it too. I'm 58 and have only recently discovered that people are basically friendly (perhaps it's because I now live in NZ!). What's more I need to be around people. So when I'm at work I'm motivated, social and happy, broadly speaking. I go home happy too.
>
> But I live alone since my wife left 4 years ago(with the kids). Every evening at first I enjoy the freedom but gradually a dread builds up. A dread and hopelessness that I'm not necessary to anyone and I'm all alone, washed up. Damn this nuclear family age. If I have to go out to play in my band I really come to life.
>
> I believe for me that this is a simpler explanation than talking about drugs and biochemical imbalance. I take Celexa but suspect it doesn't do much. Xanax is powerless over "the evening feeling" too. I sometimes have a compulsion to prove that I can go it alone in life. However I suspect none of us can, because we're social animals. Perhaps even hermits pay a high emotional price for their freedom. Or perhaps the pain of feeling alone and un-needed is less than the pain outside in the world.
>
> Life's a bugger really
>
> Fred

Fred- very well said. I agree completely. The loneliness and dread at night doesn't respond to anti-anxiety meds - it's something you can't put your finger on - but know it's there. Part of being human - if not the most important part/goal is to be intimate with other humans. We need intimacy just like we need food to survive. Without it, the loneliness eats away at us like severe hunger. At work, I'm more social and don't feel dread. But when I come home it starts sinking in - or creeping in. It doesn't help either to have friends who have abandoned you because of your mental illness as mine have done.

Thanks for the post Fred--you raised a VERY important point.
Jerry

 

Re: Why are evenings worse? » jerrympls

Posted by ed_uk on May 20, 2005, at 5:25:02

In reply to Re: Why are evenings worse? » FredPotter, posted by jerrympls on May 20, 2005, at 1:40:20

Hi Jerry,

>Part of being human - if not the most important part/goal is to be intimate with other humans.

Well said!

Warm regards,
Ed.

 

Re: Why are evenings worse?

Posted by Maxime on May 20, 2005, at 6:14:20

In reply to Re: Why are evenings worse?, posted by FredPotter on May 20, 2005, at 0:14:17

Hi Fred *hugs*

I think you are right. I am trying to find things to do at night. To go OUT and do. I have to take it slow though. I am only just coming out of my depression right now. Wish I could pop over to NZ and we could and do something together!

I will work on it. I also have myself tied up in volunteer work that involved a lot of writing and ties me to the computer. I look for jobs during the day, and work on my volunteer stuff at night. So I need to get out more period. I am going hiking on Sunday ... that should help. :-)

But I do agree with you, yet a part of me thinks some of it is biochemical. It could also be a bit of PSTD as I was attacked (badly)at night once. There are so many variables.

You are a sweetie!

Maxime

> I think you might be wrong to blame biochemistry for this. Although biochemistry will alter with mood, it may not be the cause. We're biochemical and we're social. We're physical *and* we're spiritual. But thanks Maxime for bringing this up because I have it too. I'm 58 and have only recently discovered that people are basically friendly (perhaps it's because I now live in NZ!). What's more I need to be around people. So when I'm at work I'm motivated, social and happy, broadly speaking. I go home happy too.
>
> But I live alone since my wife left 4 years ago(with the kids). Every evening at first I enjoy the freedom but gradually a dread builds up. A dread and hopelessness that I'm not necessary to anyone and I'm all alone, washed up. Damn this nuclear family age. If I have to go out to play in my band I really come to life.
>
> I believe for me that this is a simpler explanation than talking about drugs and biochemical imbalance. I take Celexa but suspect it doesn't do much. Xanax is powerless over "the evening feeling" too. I sometimes have a compulsion to prove that I can go it alone in life. However I suspect none of us can, because we're social animals. Perhaps even hermits pay a high emotional price for their freedom. Or perhaps the pain of feeling alone and un-needed is less than the pain outside in the world.
>
> Life's a bugger really
>
> Fred

 

Re: Why are evenings worse?

Posted by Maxime on May 20, 2005, at 6:22:53

In reply to Re: Why are evenings worse? » Maxime, posted by jerrympls on May 20, 2005, at 1:33:57

Jerry, I am the same way re. the summer months! Wow, I have never found anyone like me before. And it's strange because I have a harsh Canadian winter to face after the fall! But I liven up a lot. I think because it reminds me of going back to school which I always enjoyed and will be returning once again to change careers in a year. I was always happy in university, even during my graduate programme which was tough.

I also cut at night sometimes as well(ashamed). And I am anorexic so my blood sugar and energy is depleted in the evening even though I do eat around 5 pm. (nothing after 6pm is allowed).

I will be seeing a neuroendocrinologist who will be testing my hormones etc. and hopefully my cortisone levels. I think the corticosteroid I was taking for asthma for well over ten years has done some damage, but I don't know for sure. Now that I am off it, I feel much better (thanks to CK1). Although now my asthma is starting to get worse. Sigh. MY GP is going to be so angry with me for stopping, but my mood and health has improved so much.

Thanks again Jerry, as usual you are a wealth of information. :-)

Maxime


> > Hello.
> >
> > I find that my depression takes over in the evening. I try to keep myself distracted by reading or writing, but still I feel a wave of sadness come over me. If I call a friend, I still feel very alone.
> >
> > Is there a biochemical reason for this? Would it have anything to do with cortisone levels?
> >
> > Sometimes I work on CBT exercises from the Feel Good Handbook to see if it will help, but so far it hasn't.
> >
> > It really is a significant drop in my mood. When I can cry .... I do. Right now I can't cry. I don't feel any anxiety or anything just EXTREME sadness.
> > This has always been the case for me. It's like my anti-depressant just stops working.
> >
> > Anyone have any input? Sometimes I don't feel very safe at night and I end up having to call a hotline. A few nights ago I went to the hospital, only to be sent home and feeling even worse.
> >
> > Help?
> >
> > Maxime
> >
> HI Maxime
>
> I'm the same way. But I get more anxious and lonely than sad. Part of it for me, I think, is that my Dexedrine has worn off - but I also think that cortisol levels have some impact as well. If I am not mistaken, cortisol production/release? is *supposed* to taper down at night staying at lower levels throughout the night and then gradually tapering back up in the morning. I THINK?? But I wouldn't blame it all on cortisol - medication timing, hormones, melatonin function, etc all come into play. I had my cortisol levels checked pretty thoroughly a while back and they found that my levels were consistently LOW! Which kinda makes sense - since my depression is more anhedonic/lethargic, etc.
>
> I know scientists are looking at meds that stabilize the cortisol system - otherwise known as the HPA axis. My pdoc think that my HPA system is out of balance - but haven't found any suitable meds to try to get it back on track.
>
> I also notice that I get more lethargic and depressed in the spring/summer months. Exact opposite from usual SAD. Not sure why that would be? But I can certainly feel a bit of mode improvement in the Fall & Winter months.
>
> Anyway, hope this helps..
> Jerry
>

 

Re: Why are evenings worse? » jerrympls

Posted by Maxime on May 20, 2005, at 6:24:58

In reply to Re: Why are evenings worse? » FredPotter, posted by jerrympls on May 20, 2005, at 1:40:20

Amen to that Jerry. :-( I've lost so many friends. They don't bother to call me anymore or invite me anywhere. I don't blame them, but it hurts.

Maxime

> It doesn't help either to have friends who have abandoned you because of your mental illness as mine have done.
>
> Thanks for the post Fred--you raised a VERY important point.
> Jerry
>

 

Re: Why are evenings worse? » jerrympls

Posted by 4WD on May 20, 2005, at 14:26:59

In reply to Re: Why are evenings worse? » Maxime, posted by jerrympls on May 20, 2005, at 1:33:57

> HI Maxime
>
> I'm the same way. But I get more anxious and lonely than sad. Part of it for me, I think, is that my Dexedrine has worn off - but I also think that cortisol levels have some impact as well. If I am not mistaken, cortisol production/release? is *supposed* to taper down at night staying at lower levels throughout the night and then gradually tapering back up in the morning. I THINK?? But I wouldn't blame it all on cortisol - medication timing, hormones, melatonin function, etc all come into play. I had my cortisol levels checked pretty thoroughly a while back and they found that my levels were consistently LOW! Which kinda makes sense - since my depression is more anhedonic/lethargic, etc.


Jerry,

My depression is also anhedonic and lethargic. However, in the last couple of years, I have also begun to have problems with panic, anxiety and general lasting terror. My cortisol levels are consistently way way too high.

So since your levels are low and you are lethargic and feel bad at night, and my levels are high and I am scared and anxious during the day but feel good at night...doesn't it seem to follow that cortisol is possibly indeed the culprit. Or perhaps there is some other force at work which causes both effects - the type of depression AND the cortisol level.


>
> I know scientists are looking at meds that stabilize the cortisol system - otherwise known as the HPA axis. My pdoc think that my HPA system is out of balance - but haven't found any suitable meds to try to get it back on track.


Have you seen an endocrinologist?


Marsha

 

Re: Why are evenings worse? » Maxime

Posted by 4WD on May 20, 2005, at 14:35:57

In reply to Re: Why are evenings worse?, posted by Maxime on May 20, 2005, at 6:22:53

Maxime,

You might want to look at the thread "urine test to measure neurotransmitter levels" - there's a lot of stuff there about cortisol levels and depression and endocrinological testing and treatment.

I used to be anorexic (two years) and then bulimic (~30 years). I am now in recovery (for about 5-6 months). If you ever want to talk, I'm here.

Marsha


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