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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by BIGDaddyachmed69 on May 7, 2004, at 0:52:29
I've been diagnosed with depression, GAD, OCD, and social anxiety. My pdoc has me on 16 mg of Gabitril, 200 mg of Lamictal, 75 mg of Paxil CR, and 5 mg of Zyprexa. He plans on lowering the dose of Zyprexa once I'm stable on Gabitril. I was also prescribed 400 mg of Neurontin a few weeks ago, to prevent me from having seizures due to my sudden discontinuation of Xanax. My pdoc thinks that I've given up on Neurontin, but I feel that it may help my social anxiety. It is a GABA analog, and some neurons that respond to Neurontin are GABAergic. Gabitril seems to help with GAD, as it is a GABA reuptake inhibitor. I'm thinking that, considering both work on GABA...this could be a killer cocktail. Zyprexa helps minimally in regards to the OCD, but I seem to slur my speech from time to time. I also have difficulty with finding the right words to fit given situations...it's a little irritating. I'm thinking, drop Zyprexa and go for Neurontin...what do you guys think?
Posted by chemist on May 7, 2004, at 1:08:57
In reply to A potential cocktail?, posted by BIGDaddyachmed69 on May 7, 2004, at 0:52:29
> I've been diagnosed with depression, GAD, OCD, and social anxiety. My pdoc has me on 16 mg of Gabitril, 200 mg of Lamictal, 75 mg of Paxil CR, and 5 mg of Zyprexa. He plans on lowering the dose of Zyprexa once I'm stable on Gabitril. I was also prescribed 400 mg of Neurontin a few weeks ago, to prevent me from having seizures due to my sudden discontinuation of Xanax. My pdoc thinks that I've given up on Neurontin, but I feel that it may help my social anxiety. It is a GABA analog, and some neurons that respond to Neurontin are GABAergic. Gabitril seems to help with GAD, as it is a GABA reuptake inhibitor. I'm thinking that, considering both work on GABA...this could be a killer cocktail. Zyprexa helps minimally in regards to the OCD, but I seem to slur my speech from time to time. I also have difficulty with finding the right words to fit given situations...it's a little irritating. I'm thinking, drop Zyprexa and go for Neurontin...what do you guys think?
hi there, chemist here...5 mg of zyprexa is in the noise level, you are experiencing positive effects with gabatril, and the only thing that worries me is that your doctor abruptly discontinued xanax, which should be tapered very slowly. that said, the gabatril seems to be working, as does the gabapentin....you have avoided benzos - which is great - and seem to know what the efficacy of the meds you are taking is relative to your condition. i think you are spot-on, and all the best wishes, chemist
Posted by BIGDaddyachmed69 on May 7, 2004, at 1:52:59
In reply to Re: A potential cocktail? » BIGDaddyachmed69, posted by chemist on May 7, 2004, at 1:08:57
> hi there, chemist here...5 mg of zyprexa is in the noise level, you are experiencing positive effects with gabatril, and the only thing that worries me is that your doctor abruptly discontinued xanax, which should be tapered very slowly. that said, the gabatril seems to be working, as does the gabapentin....you have avoided benzos - which is great - and seem to know what the efficacy of the meds you are taking is relative to your condition. i think you are spot-on, and all the best wishes, chemist
I appreciate your support...you said that 5 mg of Zyprexa is in the noise level, what does that mean? I've read that Lamictal decreases Glutamate, but I'm not sure of the mechanism of action. I would guess that in doing so, GABA would somehow become enhanced...but again I'm not sure that's the case. I feel that GABA is a major player as far as my GAD and social anxiety goes...so I'm figuring the more meds I'm on that have an effect on GABA, the better off I am.
Posted by chemist on May 7, 2004, at 2:14:54
In reply to Re: A potential cocktail?, posted by BIGDaddyachmed69 on May 7, 2004, at 1:52:59
> > hi there, chemist here...5 mg of zyprexa is in the noise level, you are experiencing positive effects with gabatril, and the only thing that worries me is that your doctor abruptly discontinued xanax, which should be tapered very slowly. that said, the gabatril seems to be working, as does the gabapentin....you have avoided benzos - which is great - and seem to know what the efficacy of the meds you are taking is relative to your condition. i think you are spot-on, and all the best wishes, chemist
>
> I appreciate your support...you said that 5 mg of Zyprexa is in the noise level, what does that mean? I've read that Lamictal decreases Glutamate, but I'm not sure of the mechanism of action. I would guess that in doing so, GABA would somehow become enhanced...but again I'm not sure that's the case. I feel that GABA is a major player as far as my GAD and social anxiety goes...so I'm figuring the more meds I'm on that have an effect on GABA, the better off I am.hi there...i meant that your low dose of zyprexa is very unlikely to provide therapeutic efficacy in the 5 mg qd range, and as you correctly state, that anything that promtes incread GABA flooding appears to be what you need....all the best, chemist
Posted by utopizen on May 7, 2004, at 12:45:59
In reply to A potential cocktail?, posted by BIGDaddyachmed69 on May 7, 2004, at 0:52:29
Zyprexa!
Ever since Abilify, all these other atypicals seem almost as bad as resorting to Thorazine!
What's wrong with Abilify? Has your doctor tried it before resorting to the pre-Abilify meds like Zyprexa? I honestly don't know why any of these things are prescribed anymore, now that Abilify has re-defined the whole generation of new atypicals...
Posted by BIGDaddyachmed69 on May 7, 2004, at 12:53:49
In reply to Re: A potential cocktail? » BIGDaddyachmed69, posted by utopizen on May 7, 2004, at 12:45:59
Yeah...my pdoc is considering Abilify, but he warned that it may induce akathisia. I experienced akathisia on Geodon, so I'm a little skeptical. Which is better for OCD, Zyprexa or Abilify? I guess it varies from person to person, like SSRIs...
Posted by smokeymadison on May 8, 2004, at 20:36:12
In reply to Re: A potential cocktail?, posted by BIGDaddyachmed69 on May 7, 2004, at 12:53:49
Abilify has helped me tremendously with my OCD. and that is saying a lot, b/c i have pure obsessional OCD. i have never tried Zyprexa, though, so i can't compare the two for you. i have tried Risperdal, but i couldn't go high enough w/ getting sooo tired. i have tried both Gabitril and Neurontin, but never at the same time. i agree both work very well for anxiety.
This is the end of the thread.
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