Re: what the heck is a partial agonist?

Posted by jd on January 19, 2000, at 23:26:20

In reply to Re: Buspar: dopamine agonist or antagonist? (Eliz?), posted by Scott L. Schofield on January 19, 2000, at 22:09:29

I've always been pretty confused too... My basic sense is that a partial agonist stimulates a given set of receptors, but can never do so to the extent of a full agonist. Thus, if there's lots of agonist around, a partial agonist can sometimes end up working more like an antagonist (by competing with the more powerful agonist).
Neurobiology students feel free to chime in... I'm out of my depth. :-)
-jd
>
> I still can't figure out what is meant by "partial agonist". Any clues?
>
>
> - Scott

Thread

Buspar: dopamine agonist or antagonist? (Eliz?) anita 1/16/00
Re: Buspar: dopamine agonist or antagonist? (Eliz?) jd 1/17/00
Re: Buspar: dopamine agonist or antagonist? (Eliz?) Scott L. Schofield 1/19/00
Re: what the heck is a partial agonist? jd 1/19/00
Re: Buspar: dopamine agonist or antagonist? (Eliz?) JohnL 1/20/00
Re: what the heck is a partial agonist? Elizabeth 1/20/00
Re: what the heck is a partial agonist? michael 1/20/00
Re: what the heck is a partial agonist? Adam 1/20/00
Re: what the heck is a partial agonist? michael 1/20/00
Re: what the heck ? confused 1/20/00
Re: what the heck is a partial agonist? Scott L. Schofield 1/21/00
Re: what the heck is a partial agonist? Sam 1/21/00
Re: what the heck is a partial agonist? Sam 1/21/00
Re: Buspar: dopamine agonist or antagonist? (Eliz?) anita 1/22/00
Re: Buspar: dopamine agonist or antagonist? (Eliz?) jd 1/23/00
Re: Buspar: dopamine agonist or antagonist? (Eliz?) jamie 1/24/00
...
Autoreceptors (Eliz?) Sam 1/28/00

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