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Re: what the heck is a partial agonist?

Posted by Scott L. Schofield on January 21, 2000, at 8:53:17

In reply to Re: what the heck is a partial agonist?, posted by Adam on January 20, 2000, at 18:33:18

Hi Adam.


That was a wonderfully infomative explanation. I look forward to reading more of you.

> > Could someone rephrase the last sentance above, without using the words agonins & antagonist?


Let me see if I can give this a try.

An agonist is a molecule that sticks (binds) to a receptor and stimulates the the receptor to do what it was designed for. It gives the receptor a tickle.

An antagonist molecule blocks the receptor, also by binding to it. Only this time, it does not tickle it. Now that the agonist is prevented from getting to the receptor, nothing gets done. It is an inhibitor.


> > What's the net effect on the serotonin & dopamine levels/availability?

I'll leave this one to someone else. I would like to know myself.


- Scott


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poster:Scott L. Schofield thread:19073
URL: http://www.dr-bob.org/babble/20000112/msgs/19324.html