Posted by Elizabeth on May 3, 2002, at 1:13:45
In reply to LSD and Antidepressants.., posted by jay on April 26, 2002, at 18:20:56
Actually, Wellbutrin is one of the few antidepressants that don't have appreciable interactions with these psychedelics. (If you're really worried about cardiovascular effects, check your pulse every so often.)
SSRIs can greatly decrease the effects of LSD and psilocybin. Usual doses of these psychedelics often have no appreciable effect on people who are taking MAOIs. Tricyclic antidepressants and lithium sometimes have been associated with unpleasant reactions to psychedelics, and I'd avoid them in combination with these antidepressants. The information on the subject that's posted at erowid.com is pretty much consistent with what little research has been done. I don't think you have to worry about "permanent brain damage" or anything of the sort.
The Klonopin should not cause any problems for you, either. I'm not so sure about the Zyprexa. You may find that the psychedelic experience diminishes.
It's really hard for people to give accurate advice about the possible effects of psychedelics on another person, particularly if the person giving the advice hasn't ever used them before. But here's my $0.02: I think psychedelics aren't the best idea if you're actively depressed -- they're too unpredictable. If you're taking ADs and are well and stable again, though, I don't see the harm. Indeed, it's considered a good sign if you're able to enjoy the activities you enjoyed before becoming depressed. If you're somewhat better but not fully recovered...well, use your judgment. Be sure that you're feeling okay when you ingest the stuff (lots of good advice about set and setting in this thread). And try a low-end dose at first (always a good idea).
-elizabeth
poster:Elizabeth
thread:104235
URL: http://www.dr-bob.org/babble/20020425/msgs/104894.html