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Re: Seroquel Pharmacology question

Posted by SLS on June 8, 2005, at 6:07:17

In reply to Re: Seroquel Pharmacology question » SLS, posted by chess on June 7, 2005, at 20:52:01

> Hi SLS
> i'm hanging in there
> how are you?

I'm actually beginning to benefit from Trileptal! I should probably redact the exclamation mark, as I have been teased before by drugs that start working and then stop within a week. I do feel slightly better, though.

> re: seroquel
> that's why i asked about its binding to 5HT-2 receptors, antagonizing these receptors is supposed to calm a person down, SSRIs down-regulate 5HT-2 receptors after a month while seroquel directly antagonizes them on first use

> i guess my main question is whether seroquel can be taken once-a-day for anxiety since its antagonization of 5HT-2 receptors persists for more than 24 hours based on the study i found (unless someone has different info)

I didn't know that.

If I remember correctly, my doctor had me take Seroquel once a day (h.s.) at dosages over 100mg in the hopes it would exert an antidepressant effect. All it really did was to make me somewhat dysphoric and irritable.

I recently read two studies that suggested Seroquel possesses significant antidepressant properties; perhaps more than Zyprexa or Clozaril.

Because of its relatively short half-life, you would think that Cymbalta would have to be dosed twice a day. But those people whom respond best to it seem to need it only once a day.

Friggin' drugs...


- Scott


 

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poster:SLS thread:509023
URL: http://www.dr-bob.org/babble/20050606/msgs/509547.html