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Re: bupropion compared to NRI's

Posted by linkadge on November 17, 2007, at 19:51:35

In reply to Re: bupropion compared to NRI's, posted by Astounder on November 16, 2007, at 10:43:22

>The seizure risk is way overblown, I think. The >original clinical trials using instant release >Wellbutrin used up to 900 mg/d, and only causes >seizure in those with already lowered seizure >thresholds (bulimics).

I would still be carefull. I know of two individuals who developed seizure disorders after bupropion induced seizures.

>DA&NAergics are known to typically decrease both >slow wave and REM sleep, while NAergics >themselves just decrease REM. Plus constant D2 >receptor stimulation (not breaking while >sleeping), is going to cause postsynaptic >downregulation. I don't care about their effects >on attention, just mood & reward, so the >mesolimibic area is most important to me.

Well, you'll never outsmart the mesolimbic system. Its always one step ahead.


Linkadge


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URL: http://www.dr-bob.org/babble/20071115/msgs/795634.html