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Re: bupropion compared to NRI's

Posted by linkadge on November 22, 2007, at 12:04:36

In reply to Re: bupropion compared to NRI's » linkadge, posted by anonymoose on November 21, 2007, at 1:04:10

>I'm not a regular smoker or drinker, and I limit >my caffeine intake to 100mg/day, on average.

Thats good. I understand though, I often resort to using certain substances simply because I want to feel better, and because prescription antidepressants rarely work (for me).

>For a while I thought I had a sleep disorder, >because I started falling asleep in class with >increasing regularity (had a sleep test done, >which turned up no sleep irregularities). Then I >started falling asleep every time I tried to >read something. I'd been a straight-A student, >but my grades tanked and I think this >precipitated full-blown depression.

>It was only then that I was put on Zoloft (my >first psychiatric med). The first day gave me an >incredible, almost euphoric response - I felt >emotion, energy, and motivation again. But this >quickly wore off by the 2nd week. I tried >augmenting with adderall 10-20mg/day, but the >therapeutic effect pooped out after a few >months.

Same here. I had a good response to zoloft, and to a lesser extent celexa. But the brain adapts quickly.

>Over the next five years, I tried numerous >antidepressants, none of which worked. Also, I'd >go a few months on ritalin/adderall (10->20mg/day) until it pooped out and then go off a >few months before trying again.

Yeah, the stimulants can poop out quickly. If you are dealing with pure AD/HD without mood issues, they can sometimes work for a long time.

>My symptoms had been getting worse and worse >over the past few months despite being off >regular ritalin/adderall. And it wasn't until >starting Selegiline yesterday that I got any >sort of relief. So I'm pretty sure that I need >something, either the Selegiline or the Mirapex, >to keep my depressive symptoms at bay.

If you find something that helps, thats the main thing. Somtimes with these drugs there is a yin-yang theory of poop out. Ie taking an SSRI too long will throw dopamine out of whack, or taking a dopaminergic too long could throw serotonin out of whack.

>So yeah, I'm pretty sure I've got some >endogenous problem that normal measures (stress >reduction, good nutrition, etc.) can't fix by >itself.

There are some pretty helpful supplements. Ie SAMe, omega-3, and SJW are of the strongest. Many suffers get a degree of relif by augmenting with certain supplements.

You might try a tryptophan/selegiline combination, if selegiline alone poops out.

Linkadge


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URL: http://www.dr-bob.org/babble/20071115/msgs/796552.html