Posted by undopaminergic on April 16, 2008, at 18:40:35
In reply to Re: how long until you noticed effect from amantad » SLS, posted by iforgotmypassword on April 16, 2008, at 17:38:24
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> > > tangent, but i kind of fear adrenergic activity as it seems maybe or likely linked to aging (breaking down collagen, for energy of all things?),
> >
> > I didn't know that.
>
> i think i confused this. if i remember it's cortisol that apparently attacks collagen, and atomoxetine ups its levels apparently.
>I felt kind of uneasy and shivery on both reboxetine and atomoxetine, and woke up uncharacteristically early in the morning, so I did get the definite subjective impression that those drugs were stressful in some way that stimulants aren't, even though most of them are also noradrenergic; perhaps they are just less potent in that regard, or alternatively, their dopaminergic action may mitigate their noradrenergic effects.
> also, i *still* produce milk after discontinuing risperidone MONTHS ago (sept), yet much less. still kind of strange.
>How long were you using it, at at what dose? I found the side effects (feelings of weakness, fatigue, and perhaps increased anhedonia) unacceptable even at 0.5 mg, but there was no milk. Are you female? I suppose it would be a more likely side effect in that case.
>
> i also have thought about GABA, more so a month ago, but since neurontin was more than a little wierd/no epiphany, i just keep my prn of lorazepam with me... (i can never seem to get addicted to ANYTHING, which according to goldstein, is a hallmark of CFS. whew.)
>That seems the be the case for me too. I attribute it to anticipatory anhedonia, which I regard as just another aspect of dopaminergic dysfunction.
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> i should look at more GABA related stuff, but my cognitive uselessness and scattering makes me ambivalent about drugs that may cause further impairment.
>You may wish to look at theanine (L-theanine). I took 1.5-2 grams, which had a strong sedative effect - perhaps like 15 mg midazolam or more. However, after extra doses of stimulants, I began to regain full alertness and my focus as I explored theanine on PubMed was exceptionally good. Judging from that single experience, which is a bit premature, I suspect that GABA and dopamine may have synergistic effects that serve to enhance focus.
poster:undopaminergic
thread:823549
URL: http://www.dr-bob.org/babble/20080412/msgs/823652.html