Posted by Ron Hill on October 4, 2007, at 7:26:05
In reply to Re: Attn all Nardil users! » Ron Hill, posted by ace on October 4, 2007, at 1:46:36
Ace,
Sometime in the next couple of days, I plan to reply to the post you sent to me. But, for right now, I want to send you two articles regarding PEA augmentation of Nardil.
However, since the Journal of Neuropsychiatry and Clinical Neurosciences does not offer free access to their full text versions, I had to find a back door that allows us to access the full text versions of the two articles of interest.
The directions to the back door are kinda hard to explain, but here goes:
1. Click here: http://bjsm.bmj.com/cgi/content/full/35/5/342
2. Go to the bottom of the page you just pulled up, and click on Register for Access.
3. Fill out the registration information.
SIDE NOTE: Perhaps you will be automatically routed to the full text version of the “PEA and Exercise” article after registering. If so, you can skip steps 4 and 5. Also, the full title of the article is “Phenylethylamine, a possible link to the antidepressant effects of exercise?”; but I will call it “PEA and Exercise” for short.
4. Click on the link in Step 1 above.
5. Fill in your user name and password that you just got when you registered. The full text of the “PEA and Exercise” article will come up on your screen.
6. Scroll down until you get to the References section at the bottom of the “PEA and Exercise” full text article. Now we have arrived at the back door. The two articles we want are Reference 2 and Reference 3. Click on one of them.
7. The abstract of the article will come up. In the menu box on the right hand side of the page, (directly adjacent to the abstract text), click the first entry; Full Text (PDF).
8. If you’re patient, the pdf text will come up in a minute or so. If you’ve got ants in your pants, you can save 30 seconds or so by clicking [Begin manual download].
9. Read the article, then go back to the References listed in the “PEA and Exercise” article and get the second one that we want.
10. If you have time, the article that I've been calling “PEA and Exercise” is worth scanning over. Real name = "Phenylethylamine, a possible link to the antidepressant effects of exercise?"
Hey, one last thing, Ace. PEA is an OTC. I bought my here: http://www.americannutrition.com/store/UNPEA.htmlHonest, polite and helpful brick and mortar store staff, safe, fast, and no problems. I used my credit card online for extra safety.
The capsules are 250 mg, which is WAY TOO MUCH to take with Nardil. The dosages discussed in the articles are 10 to 30 mg/day in one article, and 20 to 60 mg/day in the other (if my memory is correct).
Ace, I will talk to you more about this when I respond to your post, but I do not think that PEA augmentation of your Nardil is wise for you. My gut feeling is that it would eventually make you irritable with high anxiety. Your GAD is likely not a good fit.
However, if you do decide to try it, please talk to me first. Send me a babble-mail message 'cause I do not check the board very often. Promise me that you will try to keep your dosage down around 20 or 30 mg, and NEVER go above 60 mg/day.
Start low and go slow. You're smart, do not screw yourself up and end up worse off than you are.
Monitor your blood pressure. Do you have a blood pressure measuring machine? Do you have a hypertensive antidote (e.g.; nifedipine) with you at all times? IMHO, everyone taking an MAOI like Nardil, should have both.
Nowhere in the literature do I find anyone concerned about hypertensive crisis with this PEA augmentation. However, better safe than sorry.
As I told you previously, I took it for 3 days, with excellent results. But, the withdrawal was torturous.
I attempted to estimate 10 mg dose sizes and I took them bid. To say the least, it's difficult to estimate how much 10 mg is out of a 250 mg pile.
My blood pressure jumped from my usual 110/70 to 142/84 after my first 10 mg dose, and it stayed there throughout the three day trial.
Rule #1: Nobody gets hurt!
Rule #2: Don't forget Rule #1!!I care about you, Mate. Be smart, do your p-homework before changing your meds, and don't do anything stupid.
-- Ron
Bipolar II with ultra rapid cycling (15 day cycle), and mild Obsessive Compulsive Personality Disorder (OCPD)
600 mg/day Trileptal
200 mg/day Lamictal
875 mg/day Keppra
90 mg/day Nardil
poster:Ron Hill
thread:786414
URL: http://www.dr-bob.org/babble/20070929/msgs/786799.html